Effect of Obesity and Exercise Training on Plasma Amino Acids and Amino Metabolites in American Indian Adolescents.

ABSTRACT:

Context

Amino acids (AAs) and their metabolites are altered with obesity and may be predictive of future diabetes in adults, but there are fewer studies on AAs, as well as conflicting findings on how they vary with obesity, in adolescents.

Objective

To determine whether plasma AAs vary with body composition and insulin sensitivity and are altered in response to exercise training.

Design

Cross-sectional, and an exercise intervention.

Setting

Tribal wellness center.

Participants

American Indian boys and girls, 11 to 17 years of age with obesity (Ob, n = 58) or normal weight (NW, n = 36).

Intervention

The Ob group completed 16 weeks of aerobic exercise training.

Main outcome measure

A panel of 42 plasma AAs.

Results

Compared with the NW

SUBMITTER: Short KR 

PROVIDER: S-EPMC6584131 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature