Evaluation of Early Allograft Function Using the Liver Graft Assessment Following Transplantation Risk Score Model.

ABSTRACT:

Importance

Early allograft dysfunction (EAD) following a liver transplant (LT) unequivocally portends adverse graft and patient outcomes, but a widely accepted classification or grading system is lacking.

Objective

To develop a model for individualized risk estimation of graft failure after LT and then compare the model's prognostic performance with the existing binary EAD definition (bilirubin level of ≥10 mg/dL on postoperative day 7, international normalized ratio of ≥1.6 on postoperative day 7, or aspartate aminotransferase or alanine aminotransferase level of >2000 U/L within the first 7 days) and the Model for Early Allograft Function (MEAF) score.

Design, setting, and participants

This retrospective single-center analysis used a transplant database to identify

SUBMITTER: Agopian VG 

PROVIDER: S-EPMC6584313 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature