Network-level assessment of reward-related activation in patients with ADHD and healthy individuals.

ABSTRACT:

Introduction

Reward processing is a key aspect of cognitive control processes, putatively instantiated by mesolimbic and mesocortical brain circuits. Deficient signaling within these circuits has been associated with psychopathology. We applied a network discovery approach to assess specific functional networks associated with reward processing in participants with attention-deficit/hyperactivity disorder (ADHD).

Methods

To describe task-related processes in terms of integrated functional networks, we applied independent component analysis (ICA) to task response maps of 60 healthy participants who performed a monetary incentive delay (MID) task. The resulting components were interpreted on the basis of their similarity with group-level task responses as well as their similar

SUBMITTER: von Rhein D 

PROVIDER: S-EPMC6584954 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature