PRevention of INCisional hernia after liver transplantation (PRINC trial): study protocol for a randomized controlled trial.

ABSTRACT:

Background

Incisional hernia is a common complication after liver transplantation with an incidence of 5 to 46%. Concerning non-transplant patients, a recently published meta-analysis describes a reduction of the incidence of incisional hernia of up to 85% due to prophylactic mesh replacement in elective, midline laparotomy. The aim of our study is to show a reduction of the incidence of incisional hernia after liver transplantation with minimal risk for complication.

Methods/design

This is an unblinded, randomized controlled trial comparing time to incisional hernia over a period of 12 months between patients undergoing liver transplantation and standardized abdominal closure with or without prophylactic placement of Phasix™ (Bard - Davol Inc., Warwick, RI, USA) mesh in an

SUBMITTER: Kniepeiss D 

PROVIDER: S-EPMC6585129 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature