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Non-invasive neuromodulation for migraine and cluster headache: a systematic review of clinical trials.


ABSTRACT: Non-invasive neuromodulation therapies for migraine and cluster headache are a practical and safe alternative to pharmacologics. Comparisons of these therapies are difficult because of the heterogeneity in study designs. In this systematic review of clinical trials, the scientific rigour and clinical relevance of the available data were assessed to inform clinical decisions about non-invasive neuromodulation. PubMed, Cochrane Library and ClinicalTrials.gov databases and the WHO's International Clinical Trials Registry Platform were searched for relevant clinical studies of non-invasive neuromodulation devices for migraine and cluster headache (1 January 1990 to 31 January 2018), and 71 were identified. This analysis compared study designs using recommendations of the International Headache

SUBMITTER: Reuter U 

PROVIDER: S-EPMC6585264 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature