Tasked-Based Functional Brain Connectivity in Multisensory Control of Wrist Movement After Stroke.

ABSTRACT: In this study we documented brain connectivity associated with multisensory integration during wrist control in healthy young adults, aged matched controls and stroke survivors. A novel functional MRI task paradigm involving wrist movement was developed to gain insight into the effects of multimodal sensory feedback on brain functional networks in stroke participants. This paradigm consisted of an intermittent position search task using the wrist during fMRI signal acquisition with visual and auditory feedback of proximity to a target position. We enrolled 12 young adults, 10 participants with chronic post-stroke hemiparesis, and nine age-matched controls. Activation maps were obtained, and functional connectivity networks were calculated using an independent component analysis (ICA) appro

SUBMITTER: Kalinosky BT 

PROVIDER: S-EPMC6585311 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature