Systems Bioinformatics: increasing precision of computational diagnostics and therapeutics through network-based approaches.

ABSTRACT: Systems Bioinformatics is a relatively new approach, which lies in the intersection of systems biology and classical bioinformatics. It focuses on integrating information across different levels using a bottom-up approach as in systems biology with a data-driven top-down approach as in bioinformatics. The advent of omics technologies has provided the stepping-stone for the emergence of Systems Bioinformatics. These technologies provide a spectrum of information ranging from genomics, transcriptomics and proteomics to epigenomics, pharmacogenomics, metagenomics and metabolomics. Systems Bioinformatics is the framework in which systems approaches are applied to such data, setting the level of resolution as well as the boundary of the system of interest and studying the emerging properties of

SUBMITTER: Oulas A 

PROVIDER: S-EPMC6585387 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature