Dissecting the Evolutionary Development of the Species Bifidobacterium animalis through Comparative Genomics Analyses.

ABSTRACT: Bifidobacteria are members of the gut microbiota of animals, including mammals, birds, and social insects. In this study, we analyzed and determined the pangenome of Bifidobacterium animalis species, encompassing B. animalis subsp. animalis and the B. animalis subsp. lactis taxon, which is one of the most intensely exploited probiotic bifidobacterial species. In order to reveal differences within the B. animalis species, detailed comparative genomics and phylogenomics analyses were performed, indicating that these two subspecies recently arose through divergent evolutionary events. A subspecies-specific core genome was identified for both B. animalis subspecies, revealing the existence of subspecies-defining genes involved in carbohydrate me

SUBMITTER: Lugli GA 

PROVIDER: S-EPMC6585482 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature