Controlled attenuation parameter does not predict hepatic decompensation in patients with advanced chronic liver disease.

ABSTRACT:

Background & aims

Assessment of hepatic steatosis by transient elastography (TE)-based controlled attenuation parameter (CAP) might predict hepatic decompensation. Therefore, we aimed to evaluate the prognostic value of CAP in patients with compensated advanced chronic liver disease (cACLD) and decompensated cirrhosis (DC).

Methods

A total of 430 patients who underwent TE (liver stiffness ≥10 kPa) and CAP measurements were included in this retrospective analysis. Half of patients (n = 189) underwent simultaneous HVPG measurement. In cACLD patients, first hepatic decompensation was defined by new onset of ascites, hepatic encephalopathy or variceal bleeding. In patients with DC, the following events were considered as further hepatic decompensation: requirement of paracentesi

SUBMITTER: Scheiner B 

PROVIDER: S-EPMC6585636 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature