Evaluation of dehydrated human umbilical cord biological properties for wound care and soft tissue healing.

ABSTRACT: Chronic wounds are a significant health care problem with serious implications for quality of life because they do not properly heal and often require therapeutic intervention. Amniotic membrane allografts have been successfully used as a biologic therapy to promote soft tissue healing; however, the umbilical cord, another placental-derived tissue, has also recently garnered interest because of its unique composition but similar placental tissue origin. The aim of this study was to characterize PURION® PLUS Processed dehydrated human umbilical cord (dHUC) and evaluate the biological properties of this tissue that contribute to healing. This was performed through the characterization of the tissue composition, evaluation of in vitro cellular response to dHUC treatment, and in vivo bioresorp

SUBMITTER: Bullard JD 

PROVIDER: S-EPMC6585686 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature