Structure, dissolution behavior, cytocompatibility, and antibacterial activity of silver-containing calcium phosphate invert glasses.

ABSTRACT: Novel CaO-P₂ O₅ -Nb₂ O₅ -Ag₂ O invert glasses with substitution Ag₂ O for Nb₂ O₅ were successfully prepared using a melt-quenching method. Ag₂ O in the glasses act as a network modifier oxide, playing the same role as Na₂ O, which breaks the phosphate chains. Analysis of the ultraviolet-visible absorption spectra of the glasses showed that the glass matrix contained ionic silver species and silver nanoparticles. Approximately 0.05 mM of Nb⁵⁺ ions released from the glasses, which would be expected to stimulate osteoblast differentiation. A glass containing 1 mol % Ag₂ O showed a linear increase in the releasing amount of Ag⁺ ions with increasing soak

SUBMITTER: Lee S 

PROVIDER: S-EPMC6585736 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature