Venous thromboembolism risk stratification for patients with lower limb trauma and cast or brace immobilization.

ABSTRACT:

Background

Thromboprophylaxis for patients with non-surgical isolated lower-limb trauma requiring immobilization is a matter of debate. Our aim was to develop and validate a clinical risk- stratification model based on Trauma, Immobilization and Patients' characteristics (the TIP score).

Methods

The TIP score criteria and the cut-off were selected by a consensus of international experts (n = 27) using the Delphi method. Retrospective validation was performed in a population-based case-control study (MEGA study). The potential score's impact in anticoagulant treatment was assessed in a prospective single-center observational cohort study.

Findings

After four successive rounds, 30 items constituting the TIP score were selected: thirteen items for trauma, three for immob

SUBMITTER: Douillet D 

PROVIDER: S-EPMC6586277 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature