A clinical decision rule to predict intracranial hypertension in severe traumatic brain injury.

ABSTRACT:

Objective

While existing guidelines support the treatment of intracranial hypertension in severe traumatic brain injury (TBI), it is unclear when to suspect and initiate treatment for high intracranial pressure (ICP). The objective of this study was to derive a clinical decision rule that accurately predicts intracranial hypertension.

Methods

Using Delphi methods, the authors identified a set of potential predictors of intracranial hypertension and a clinical decision rule a priori by consensus among a group of 43 neurosurgeons and intensivists who have extensive experience managing severe TBI without ICP monitoring. To validate these predictors, the authors used data from a Latin American trial (n = 150; BEST TRIP). To report on the performance of the rule, they calculated

SUBMITTER: Alali AS 

PROVIDER: S-EPMC6586526 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature