On measuring nanoparticle toxicity and clearance with Paramecium caudatum.

ABSTRACT: As the extent to which aquatic environments are polluted with nano-scale objects is becoming known, we are presented with an urgent need to study their effects on various forms of life and to clear and/or detoxify them. A range of methods exist to these ends, but a lack of inter-study comparability arising from an absence of experimental standardisation impedes progress. Here we present experiments that demonstrate measurement of orchestrated uptake and clearance of two environmentally-relevant nano- and micromaterials by a model aquatic microoraganism, Paramecium caudatum. Experiments were based on a simple, modular, multi-chamber platform that permits standardised control of organism behaviour and measurement of variables relevant to the study of nanotoxicology, including nanomaterial ch

SUBMITTER: Mayne R 

PROVIDER: S-EPMC6586663 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature