Ontology highlight
ABSTRACT:
SUBMITTER: Villanueva JE
PROVIDER: S-EPMC6586848 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Villanueva Jesús E JE Livelo Christopher C Trujillo Adriana S AS Chandran Sahaana S Woodworth Brendon B Andrade Leo L Le Hiep D HD Manor Uri U Panda Satchidananda S Melkani Girish C GC
Nature communications 20190620 1
Pathological obesity can result from genetic predisposition, obesogenic diet, and circadian rhythm disruption. Obesity compromises function of muscle, which accounts for a majority of body mass. Behavioral intervention that can counteract obesity arising from genetic, diet or circadian disruption and can improve muscle function holds untapped potential to combat the obesity epidemic. Here we show that Drosophila melanogaster (fruit fly) subject to obesogenic challenges exhibits metabolic disease ...[more]