Test-retest reliability of time-frequency measures of auditory steady-state responses in patients with schizophrenia and healthy controls.

ABSTRACT:

Background

Auditory steady-state response (ASSR) paradigms have consistently demonstrated gamma band abnormalities in schizophrenia at a 40-Hz driving frequency with both electroencephalography (EEG) and magnetoencephalography (MEG). Various time-frequency measures have been used to assess the 40-Hz ASSR, including evoked power, single trial total power, phase-locking factor (PLF), and phase-locking angle (PLA). While both EEG and MEG studies have shown power and PLF ASSR measures to exhibit excellent test-retest reliability in healthy adults, the reliability of these measures in patients with schizophrenia has not been determined.

Methods

ASSRs were obtained by recording EEG data during presentation of repeated 20-Hz, 30-Hz and 40-Hz auditory click trains from nine schizoph

SUBMITTER: Roach BJ 

PROVIDER: S-EPMC6587022 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature