Ontology highlight
ABSTRACT:
SUBMITTER: McDermott DH
PROVIDER: S-EPMC6587139 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
McDermott David H DH Heusinkveld Lauren E LE Zein Wadih M WM Sen H Nida HN Marquesen Martha M MM Parta Mark M Rosenzweig Sergio D SD Fahle Gary A GA Keller Michael D MD Wiley Henry E HE Murphy Philip M PM
F1000Research 20190102
A patient with WHIM syndrome immunodeficiency presented with sudden painless right eye blindness associated with advanced retinal and optic nerve damage. <i>Toxoplasma gondii</i> was detected by PCR in vitreous fluid but not serum. The patient was treated with pyrimethamine/sulfadiazine for 6 weeks due to evidence of active ocular inflammation and then received prophylaxis with trimethoprim-sulfamethoxazole due to his immunosuppression. Vision did not return; however, the infection did not spr ...[more]