Effect of Universal Testing and Treatment on HIV Incidence - HPTN 071 (PopART).

ABSTRACT:

Background

A universal testing and treatment strategy is a potential approach to reduce the incidence of human immunodeficiency virus (HIV) infection, yet previous trial results are inconsistent.

Methods

In the HPTN 071 (PopART) community-randomized trial conducted from 2013 through 2018, we randomly assigned 21 communities in Zambia and South Africa (total population, approximately 1 million) to group A (combination prevention intervention with universal antiretroviral therapy [ART]), group B (the prevention intervention with ART provided according to local guidelines [universal since 2016]), or group C (standard care). The prevention intervention included home-based HIV testing delivered by community workers, who also supported linkage to HIV care and ART adherence. The pr

SUBMITTER: Hayes RJ 

PROVIDER: S-EPMC6587177 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature