Wet/Sono-Chemical Synthesis of Enzymatic Two-Dimensional MnO₂ Nanosheets for Synergistic Catalysis-Enhanced Phototheranostics.

ABSTRACT: 2D nanomaterials have attracted broad interest in the field of biomedicine owing to their large surface area, high drug-loading capacity, and excellent photothermal conversion. However, few studies report their "enzyme-like" catalytic performance because it is difficult to prepare enzymatic nanosheets with small size and ultrathin thickness by current synthetic protocols. Herein, a novel one-step wet-chemical method is first proposed for protein-directed synthesis of 2D MnO₂ nanosheets (M-NSs), in which the size and thickness can be easily adjusted by the protein dosage. Then, a unique sono-chemical approach is introduced for surface functionalization of the M-NSs with high dispersity/stability as well as metal-cation-chelating capacity, which can not only chelate ⁶⁴

SUBMITTER: Tang W 

PROVIDER: S-EPMC6587182 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature