The unmet need for better risk stratification of non-proliferative diabetic retinopathy.

ABSTRACT: Diabetic retinopathy is a common microvascular complication of diabetes and remains one of the leading causes of preventable blindness in working-age people. Non-proliferative diabetic retinopathy is the earliest stage of diabetic retinopathy and is typically asymptomatic. Currently, the severity of diabetic retinopathy is assessed using semi-quantitative grading systems based on the presence or absence of retinal lesions. These methods are well validated, but do not predict those at high risk of rapid progression to sight-threatening diabetic retinopathy; therefore, new approaches for identifying these people are a current unmet need. We evaluated published data reporting the lesion characteristics associated with different progression profiles in people with non-proliferative diabetic re

SUBMITTER: Sivaprasad S 

PROVIDER: S-EPMC6587728 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature