Quantitative resistance to clubroot infection mediated by transgenerational epigenetic variation in Arabidopsis.

ABSTRACT: Quantitative disease resistance, often influenced by environmental factors, is thought to be the result of DNA sequence variants segregating at multiple loci. However, heritable differences in DNA methylation, so-called transgenerational epigenetic variants, also could contribute to quantitative traits. Here, we tested this possibility using the well-characterized quantitative resistance of Arabidopsis to clubroot, a Brassica major disease caused by Plasmodiophora brassicae. For that, we used the epigenetic recombinant inbred lines (epiRIL) derived from the cross ddm1-2 × Col-0, which show extensive epigenetic variation but limited DNA sequence variation. Quantitative loci under epigenetic control (QTL^epi ) mapping was carried out on 123 epiRIL infected with P. brassicae and usi

SUBMITTER: Liegard B 

PROVIDER: S-EPMC6587750 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature