Abnormal phasic activity in saliency network, motor areas, and basal ganglia in Parkinson's disease during rhythm perception.

ABSTRACT: Behavioral studies indicate that persons with Parkinson's disease have complexity dependent problems with the discrimination of auditory rhythms. Furthermore, neuroimaging studies show that rhythm processing activates many brain areas that overlap with areas affected by Parkinson's disease (PD). This study sought to investigate the neural correlates of rhythm processing in PD and healthy controls, with a particular focus on rhythmic complexity. We further aimed to investigate differences in brain activation during initial phases of rhythm processing. Functional magnetic resonance imaging was used to scan 15 persons with Parkinson's disease and 15 healthy controls while they listened to musical rhythms with two different levels of complexity. Rhythmic complexity had no significant effect on

SUBMITTER: Vikene K 

PROVIDER: S-EPMC6587836 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature