Proton MRS of cervical cancer at 7 T.

ABSTRACT: The differentiation grade of cervical cancer is histologically assessed by examining biopsies or surgical specimens. MRS is a highly sensitive technique that images tissue metabolism and can be used to increase the specificity of tissue characterization in a non-invasive manner. We aim to explore the feasibility of using in vivo ¹ H-MRS at 7 T in women with cervical cancer to study tissue fatty acid composition. 10 women with histologically proven Stage IB1-IIB cervical cancer were scanned with a whole-body 7 T MR system with a multi-transmit system and an internal receive only monopole antenna. A STEAM sequence was used to obtain ¹ H-MRS data. Fatty acid resonances were fitted with Lorentzian curves and the 2.1 ppm/1.3 ppm ratios were calculated. ¹ H-MRS d

SUBMITTER: Arteaga de Castro CS 

PROVIDER: S-EPMC6588007 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature