Ontology highlight
ABSTRACT:
SUBMITTER: Kim KS
PROVIDER: S-EPMC6588159 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Molecular pharmaceutics 20180829 10
We provide immense insulin absorption from the gastrointestinal tract, combining apical sodium-dependent bile acid transporter-mediated intestinal uptake and the lymphatic transport pathway. This strategy has proven to employ chondroitin sulfate- g-taurocholic acid coated, insulin-loaded partially uncapped liposome (IPUL-CST) for type 1 diabetes mellitus (T1DM) treatment. The loading efficiency of insulin in IPUL-CST increased significantly from 33% to 75% via the partially uncapped liposome pre ...[more]