Dataset Information

Tobacco consumption and premenstrual syndrome: A case-control study.

ABSTRACT:

Objective

To assess whether tobacco smoking is associated with Premenstrual Syndrome (PMS) and its most severe form, Premenstrual Dysphoric Disorder (PMDD).

Design

Case-control study with incident cases using the Spanish public healthcare system.

Setting

3 major public hospitals and one family counseling and planning center.

Population

Women consulting for troubles related to menstruation and for other motives such as screening for uterine cancer, contraception counseling or desire for pregnancy.

Methods

Logistic regression.

Main outcome measures

Odds Ratios of PMS and PMDD.

Results

285 incident PMS cases and 285 age-matched controls on the one hand, and 88 incident PMDD cases and 176 controls on the other hand participated in the study. The odds of premenstrual disorders was higher in current smokers compared with never smokers: Odds Ratio (OR) = 1.78, 95% Confidence Interval (CI): 1.20-2.63 for PMS and OR = 2.92, 95%CI: 1.55-5.50 for PMDD. For PMS, women who smoke 1 to 5 cigarettes/day presented an OR = 2.82, 95%CI: 1.57-5.06 and those who smoke more than 15 cigarettes/day an OR = 2.52, 95%CI: 0.99-6.40. Compared to non-smokers, current and ex-smokers who smoked < 3 pack-years presented an OR = 1.79, 95%CI: 1.04-3.08 for PMS, and an OR = 3.06, 95%CI: 1.27-7.35 for PMDD. Smokers of 3 to 8 pack-years presented an OR = 2.34, 95%CI: 1.33-4.13 for PMS and OR = 3.56, 95%CI: 1.55-8.17 for PMDD. These results were confirmed by the exposure-effect curve obtained from a cubic spline model.

Conclusions

This study shows that smokers are more likely to develop PMS and PMDD.

SUBMITTER: Fernandez MDM

PROVIDER: S-EPMC6588233 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Tobacco consumption and premenstrual syndrome: A case-control study.

Fernández María Del Mar MDM Montes-Martínez Agustín A Piñeiro-Lamas María M Regueira-Méndez Carlos C Takkouche Bahi B

PloS one 20190621 6

<h4>Objective</h4>To assess whether tobacco smoking is associated with Premenstrual Syndrome (PMS) and its most severe form, Premenstrual Dysphoric Disorder (PMDD).<h4>Design</h4>Case-control study with incident cases using the Spanish public healthcare system.<h4>Setting</h4>3 major public hospitals and one family counseling and planning center.<h4>Population</h4>Women consulting for troubles related to menstruation and for other motives such as screening for uterine cancer, contraception couns ...[more]

PMID: 31226148

Similar Datasets

Project description:BackgroundPancreatic cancer is a deadly malignancy with limited screening and few modifiable risk factors. The objective of this study was to investigate the association between a modifiable lifestyle behavior, cruciferous vegetable consumption, and pancreatic cancer, both overall and by subgroups based on non-modifiable, established risk factors.MethodsWe conducted a hospital-based, case-control study utilizing data from the Patient Epidemiology Data System (1982-1998) at Roswell Park Comprehensive Cancer Center (Buffalo, NY) which included 183 pancreatic cancer patients and 732 cancer-free controls. Data were collected using a self-administered questionnaire including a 52-item food frequency questionnaire and other epidemiologic data. Multivariable logistic regression, adjusted for age, body mass index (BMI), sex, smoking status, total meat, and family history of pancreatic cancer, was used to estimate odds ratios (OR) and 95% confidence intervals (CI) for the associations between cruciferous vegetable consumption and pancreatic cancer. Subgroup analyses were conducted by sex, smoking status, and BMI.ResultsWe observed inverse associations between cruciferous vegetable intake and pancreatic cancer, with a significant 40% lower odds of pancreatic cancer among subjects consuming >1.5 servings per week (SPW) of raw cruciferous vegetables compared to those consuming less than 0.5 SPW (OR = 0.60, 95% CI: 0.39-0.93). Each additional SPW of total, raw, and cooked cruciferous vegetables was associated with a significant 7-15% lower odds of pancreatic cancer, with the strongest association seen in raw cruciferous vegetables (OR = 0.85, 95% CI: 0.75-0.95). We observed inverse associations between raw cruciferous vegetable intake and pancreatic cancer among people who were overweight, former smokers, and males, ranging from 50% to 59% lower odds.ConclusionConsuming cruciferous vegetables, especially raw cruciferous vegetables, is a modifiable lifestyle behavior which may be inversely associated with pancreatic cancer, including among subgroups with other non- or not easily modifiable risk factors for this deadly malignancy.

Dataset Information

Tobacco consumption and premenstrual syndrome: A case-control study.

Objective

Design

Setting

Population

Methods

Main outcome measures

Results

Conclusions

Publications

Tobacco consumption and premenstrual syndrome: A case-control study.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets