Essential amino acid-enriched meal replacement promotes superior net protein balance in older, overweight adults.

ABSTRACT:

Background & aims

Older individuals are susceptible to the loss of muscle and accumulation of fat. To address this problem, we have compared protein kinetics following consumption of an essential amino acid (EAA)-enriched meal replacement (EMR) to consumption of a high-protein meal replacement beverage (Bariatric Advantage, BA) using stable isotope methodology.

Methods

Eight older (67 ± 2), obese (35 ± 2 kg/m²) female and male participants completed two studies using a randomized, crossover design in which they ingested each meal replacement. The isotopic tracers L-[²H₅]phenylalanine & L-[²H₂]tyrosine were delivered via primed, continuous intravenous infusion throughout a basal period and following consumption of EMR or

SUBMITTER: Coker RH 

PROVIDER: S-EPMC6588419 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature