Periprocedural Bridging in Patients with Venous Thromboembolism: A Systematic Review.

ABSTRACT:

Background

Vitamin K antagonists (VKA) are the most widely used anticoagulants, and bridging is commonly administered during periprocedural VKA interruption. Given the unclear benefits and risks of periprocedural bridging in patients with previous venous thromboembolism, we aimed to assess recurrent venous thromboembolism and bleeding outcomes with and without bridging in this population.

Methods

We performed a systematic review searching the PubMed and Embase databases from inception to December 7, 2017 for randomized and nonrandomized studies that included adults with previous venous thromboembolism requiring VKA interruption to undergo an elective procedure, and that reported venous thromboembolism or bleeding outcomes. Quality of evidence was graded by consensus.

Resu

SUBMITTER: Baumgartner C 

PROVIDER: S-EPMC6588421 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature