A retrospective analysis of the use of intravenous dexamethasone for postoperative nausea and vomiting in total joint replacement.

ABSTRACT:

Background

Multimodal perioperative pain-management protocols have contributed to the success of elective total joint replacement in orthopedic surgery. General or neuraxial anesthesia for arthroplasty is accompanied by complications such as pruritis, nausea, and vomiting. Dexamethasone has been demonstrated to be a safe perioperative antiemetic. This study evaluates the benefit of low-dose intravenous dexamethasone used in the perioperative period to prevent postoperative nausea and vomiting.

Methods

Two scheduled doses of 8 mg of dexamethasone 12 hours apart after total hip arthroplasty or total knee arthroplasty were given to a dexamethasone group (n = 492) and were retrospectively compared with a no-dexamethasone group (n = 364) based on the use of antiemetics in the pos

SUBMITTER: Bustos FP 

PROVIDER: S-EPMC6588720 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature