Dual antiplatelet therapy following percutaneous coronary intervention: protocol for a systematic review.

ABSTRACT:

Introduction

Dual antiplatelet therapy (DAPT) is routinely given to patients after percutaneous coronary intervention (PCI) with stenting; however, there is ongoing debate about the optimal duration, especially in specific patient groups. In the proposed systematic review, we intend to assess the optimal duration of DAPT following PCI with stenting, with a focus on clinically relevant patient subgroups.

Methods and analysis

We will perform a comprehensive search of the published literature for randomised controlled trials (RCTs) assessing the benefits and harms of extended DAPT (>12 months) compared with short-term DAPT (6-12 months) following PCI with stenting (bare metal or drug eluting). ClinicalTrials.gov and ICTRP will also be searched to identify ongoing and completed

SUBMITTER: Elliott J 

PROVIDER: S-EPMC6588972 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature