The validity of central venous to arterial carbon dioxide difference to predict adequate fluid management during living donor liver transplantation. A prospective observational study.

ABSTRACT:

Background

To assess the validity of central and pulmonary veno-arterial CO₂ gradients to predict fluid responsiveness and to guide fluid management during liver transplantation.

Methods

In adult recipients (ASA III to IV) scheduled for liver transplantation, intraoperative fluid management was guided by pulse pressure variations (PPV). PPV of ≥15% (Fluid Responding Status-FRS) indicated fluid resuscitation with 250 ml albumin 5% boluses repeated as required to restore PPV to < 15% (Fluid non-Responding Status-FnRS). Simultaneous blood samples from central venous and pulmonary artery catheters (PAC) were sent to calculate central venous to arterial CO₂ gap [C(v-a) CO2 gap] and pulmonary venous to arterial CO₂ gap [Pulm(p-a) CO2 gap]. CO and l

SUBMITTER: ELAyashy M 

PROVIDER: S-EPMC6589166 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature