Dataset Information

Effects of obesity on the lipid and metabolite profiles of young adults by serum ¹H-NMR spectroscopy.

ABSTRACT:

Background

Overweight (OW) is considered a risk for various metabolic diseases. However, its effects as a mechanism that alters the metabolite profiles remain unclear. The purpose of this study is to investigate the effects that OW has on the lipid and metabolite profiles in young adults.

Methods

The serum metabolite profiles of 46 young adults of normal weight and those considered OW were studied by Proton nuclear magnetic resonance spectroscopy (¹H NMR) technique.

Results

¹H NMR metabolite analysis shows the alteration of metabolic levels and increased levels of CH₂ lipids and CH₃ lipids, which are used as unique biomarkers to identify OW subjects from the normal weight groups.

Conclusion

This present study reveals that OW contributes to the systemic metabolism and the metabolite alteration among young adults. The alteration in serum lipids level could shed the light on metabolic syndrome pathogenesis in young adults and needs further elucidation.

SUBMITTER: Pasanta D

PROVIDER: S-EPMC6589329 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Publications

Effects of obesity on the lipid and metabolite profiles of young adults by serum <sup>1</sup>H-NMR spectroscopy.

Pasanta Duanghathai D Chancharunee Sirirat S Tungjai Montree M Kim Hong Joo HJ Kothan Suchart S

PeerJ 20190620

<h4>Background</h4>Overweight (OW) is considered a risk for various metabolic diseases. However, its effects as a mechanism that alters the metabolite profiles remain unclear. The purpose of this study is to investigate the effects that OW has on the lipid and metabolite profiles in young adults.<h4>Methods</h4>The serum metabolite profiles of 46 young adults of normal weight and those considered OW were studied by Proton nuclear magnetic resonance spectroscopy (<sup>1</sup>H NMR) technique.<h4> ...[more]

PMID: 31259100

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Dataset Information

Effects of obesity on the lipid and metabolite profiles of young adults by serum ¹H-NMR spectroscopy.

Background

Methods

Results

Conclusion

Publications

Effects of obesity on the lipid and metabolite profiles of young adults by serum <sup>1</sup>H-NMR spectroscopy.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets

Dataset Information

Effects of obesity on the lipid and metabolite profiles of young adults by serum 1H-NMR spectroscopy.

Background

Methods

Results

Conclusion

Publications

Effects of obesity on the lipid and metabolite profiles of young adults by serum <sup>1</sup>H-NMR spectroscopy.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets

Effects of obesity on the lipid and metabolite profiles of young adults by serum ¹H-NMR spectroscopy.