Vaginal Glycogen, Not Estradiol, Is Associated With Vaginal Bacterial Community Composition in Black Adolescent Women.

ABSTRACT: PURPOSE:The purpose of this study was to characterize the composition of vaginal bacterial communities in a cohort of black adolescent women and to determine how the species composition of these communities correlates with levels of estradiol, glycogen, and stress. METHODS:Twenty-one black adolescent women were sampled longitudinally. The composition of their vaginal communities was determined by analyzing the sequences of the V1-V3 regions of 16S rRNA genes, and they were grouped based on patterns in species abundances. The relationships between estradiol, glycogen, psychosocial stress, and the composition of these communities were assessed. RESULTS:Vaginal communities could be distinguished and classified into three groups that differed in the abundances of Lactobacillus. Eighty-one perc

SUBMITTER: Nunn KL 

PROVIDER: S-EPMC6589382 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature