Gestational diabetes and adiposity are independent risk factors for perinatal outcomes: a population based cohort study in Sweden.

ABSTRACT:

Aims

To evaluate the interaction effects of gestational diabetes (GDM) with obesity on perinatal outcomes.

Methods

A population-based cohort study in Sweden excluding women without pre-gestational diabetes with a singleton birth between 1998 and 2012. Logistic regression was performed to evaluate the potential independent associations of GDM and BMI with adverse perinatal outcomes as well as their interactions. Main outcome measures were malformations, stillbirths, perinatal mortality, low Apgar score, fetal distress, prematurity and Erb's palsy.

Results

Some 1,294,006 women were included, with a GDM prevalence of 1% (n = 14,833). The rate of overweight/obesity was 67.7% in the GDM-group and 36.1% in the non-GDM-group. No significant interaction existed. Offspring of

SUBMITTER: Hilden K 

PROVIDER: S-EPMC6590111 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature