Serum markers of B-cell activation in pregnancy during late gestation, delivery, and the postpartum period.

ABSTRACT:

Problem

B cells are vital for the normal evolution of pregnancy due to their humoral and possible regulatory activities. Our group and others have documented that circulating B-cell subsets undergo changes from normal late pregnancy to the postpartum period. However, the underlying mechanisms are poorly understood. Therefore, this study examined the degree of B-cell activation in normal pregnancy by analyzing the levels of serum markers in healthy pregnant women during the third trimester of pregnancy, the day of delivery, and the postpartum period.

Method of study

A prospective study including pregnant and non-pregnant women attending routine care was undertaken at a hospital clinic. Sociodemographic and clinical data were collected, along with peripheral blood samples. The

SUBMITTER: Lima J 

PROVIDER: S-EPMC6590212 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature