Trends in liver transplantation for primary biliary cholangitis in Europe over the past three decades.

ABSTRACT:

Background

The importance of primary biliary cholangitis as an indication for liver transplantation has probably been influenced by the introduction of therapies, and changes in selection criteria and disease epidemiology.

Aims

To assess the time trends in liver transplantation for primary biliary cholangitis and to evaluate the characteristics of the patient population during the past three decades.

Methods

Patients undergoing liver transplantation from 1986 to 2015 in centres reporting to the European Liver Transplantation Registry were included. We excluded combined organ transplantations and patients <18 years. Trends were assessed using linear regression models.

Results

We included 112 874 patients, of whom 6029 (5.3%) had primary biliary cholangitis. Afte

SUBMITTER: Harms MH 

PROVIDER: S-EPMC6590354 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature