Association of diabetes treatment with long-term glycemic patterns in patients with type 2 diabetes mellitus: A prospective cohort study.

ABSTRACT:

Aim

This study aimed to analyze diabetes treatment and treatment changes in association with long-term glycemic patterns in an Asian population with diabetes.

Materials and methods

This was a prospective cohort study of 6218 patients with type 2 diabetes managed in public primary care clinics in Singapore. Clinical data from 2011 to 2016 were extracted from electronic medical records, including serial HbA1c measurements and dispensed antidiabetic medication records. Patterns of longitudinal HbA1c trajectories were identified using latent class growth analysis, and patients' annual treatment plans were compared between subgroups with different HbA1c patterns.

Results

We identified four distinct HbA1c patterns. Eighty-one percent of patients were classified in the low-s

SUBMITTER: Luo M 

PROVIDER: S-EPMC6590368 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature