Cytokine profiles of phakic and pseudophakic eyes with primary retinal detachment.

ABSTRACT:

Purpose

To compare the cytokine profiles of phakic (p) and pseudophakic (ps) eyes with primary rhegmatogenous retinal detachment (RD) to eyes with macular holes (MH) and to identify differences in the specific cytokine profiles.

Methods

Aqueous humour (AH) and vitreous fluid (VF) were obtained from patients with primary RD without proliferative vitreoretinopathy undergoing vitrectomy. AH and VF of patients with macular holes (MH) served as controls. Forty-three different cytokines were quantified using multiplex cytokine analysis. Intergroup and intragroup comparisons were performed. To control for multiple comparisons, Holm's correction was applied.

Results

VF and AH samples of 71 eyes with RD (pRD N = 38; psRD N = 33) and 26 eyes with MH were included. Cytokine leve

SUBMITTER: Garweg JG 

PROVIDER: S-EPMC6590374 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature