Response patterns of routinely measured inflammatory and coagulatory parameters in sepsis.

ABSTRACT:

Background

Sepsis is characterized by a pro-inflammatory and pro-coagulatory shift which can induce life-threatening complications. Close monitoring and risk stratification of sepsis patients is crucial for proper treatment and consequently patient outcome. Therefore, this study focuses on the response patterns of inflammatory and coagulatory parameters used in clinical routines to estimate the course of sepsis.

Methods

A total of 1,110 patients diagnosed with sepsis were retrospectively analyzed to identify response patterns for risk stratification of routine parameters measured at the peak level of C-reactive protein. Cluster analysis was used and the differences in the patient characteristics and 28-day survival were assessed. Cox proportional hazards regression model for

SUBMITTER: Bachler M 

PROVIDER: S-EPMC6590445 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature