A report of two children with Gorham-Stout disease.

ABSTRACT:

Background

Gorham-Stout disease is a rare condition characterized by unifocal and massive type IV osteolysis (variant of idiopathic nonhereditary osteolytic disease) with a slow progression, which is self-limiting for some years. It is characterized by recurrent vascular tumors with disruption of the anatomical architecture and intraosseous proliferation of vascular channels that leads to the destruction and resorption of the bone matrix. The aim of this study is to present the clinical features of this disease, as well as the importance of prompt diagnosis and treatment, with a review of the reported cases.

Case reports

We describe two cases of Gorham-Stout disease between 2013 and 2017 with surgical interventions, follow-up and results. Case one involves an 11-year-old mal

SUBMITTER: Tena-Sanabria ME 

PROVIDER: S-EPMC6591827 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature