Novel encephalomyelitis-associated astrovirus in a muskox (Ovibos moschatus): a surprise from the archives.

ABSTRACT:

Background

The small, single-stranded positive-sense RNA astroviruses are mostly known to be enteric viruses. In recent years, though, different astroviruses were reported in association with neurological disease in various species. In cattle, two distinct neurotropic astrovirus genotype species were described in numerous cases of nonsuppurative encephalomyelitis, with one of these viruses also reported in similar circumstances in several sheep. Here, we retrieved archived formalin-fixed, paraffin-embedded brain tissues of a muskox diagnosed with a comparable disease pattern in 1982 and investigated them for the presence of neurotropic astroviruses with various techniques.

Results

Initially, tissue samples scored positive for both neurotropic astroviruses by immunohistochemi

SUBMITTER: Boujon CL 

PROVIDER: S-EPMC6591865 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature