Comparative analysis of apicoplast genomes of Babesia infective to small ruminants in China.

ABSTRACT:

Background

Babesiosis is an economically important disease caused by tick-borne apicomplexan protists of the genus Babesia. Most apicomplexan parasites, including Babesia, have a plastid-derived organelle termed an apicoplast, which is involved in critical metabolic pathways such as fatty acid, iron-sulphur, haem and isoprenoid biosynthesis. Apicoplast genomic data can provide significant information for understanding and exploring the biological features, taxonomic and evolutionary relationships of apicomplexan parasites, and identify targets for anti-parasitic drugs. However, there are limited data on the apicoplast genomes of Babesia species infective to small ruminants.

Methods

PCR primers were designed based on the previously reported apicoplast genome sequences of Babe

SUBMITTER: Wang X 

PROVIDER: S-EPMC6591869 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature