Assessing the cost-effectiveness of HPV vaccination strategies for adolescent girls and boys in the UK.

ABSTRACT:

Background

Human papillomavirus (HPV) is the most widespread sexually transmitted infection worldwide. It causes several health consequences, in particular accounting for the majority of cervical cancer cases in women. In the United Kingdom, a vaccination campaign targeting 12-year-old girls started in 2008; this campaign has been successful, with high uptake and reduced HPV prevalence observed in vaccinated cohorts. Recently, attention has focused on vaccinating both sexes, due to HPV-related diseases in males (particularly for high-risk men who have sex with men) and an equity argument over equalising levels of protection.

Methods

We constructed an epidemiological model for HPV transmission in the UK, accounting for nine of the most common HPV strains. We complemented this

SUBMITTER: Datta S 

PROVIDER: S-EPMC6591963 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature