Rod-shape MSN@MoS₂ Nanoplatform for FL/MSOT/CT Imaging-Guided Photothermal and Photodynamic Therapy.

ABSTRACT: Rod-shape nanoplatform have received tremendous attention owing to their enhanced ability for cell internalization and high capacity for drug loading. MoS₂, widely used in electronic devices, electrocatalysis, sensor and energy-storage, has been studied as photothermal agents over the years. However, the efficacy of rod-shape MoS₂ based photothermal agents for photothermal therapy has not been studied before. Here, a near-infrared (NIR) light-absorbing MoS₂ nanosheets coated mesoporous silica nanorods with human serum albumin (HSA) modifying and Ce6 loading (MSNR@MoS₂-HSA/Ce6) were constructed for combined photothermal and photodynamic therapy. Methods: The near-infrared (NIR) light was used to trigger the synergistic anti-tumor therapy. I

SUBMITTER: Yang L 

PROVIDER: S-EPMC6592168 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature