Individual differences in TMS sensitivity influence the efficacy of tDCS in facilitating sensorimotor adaptation.

ABSTRACT: BACKGROUND:Transcranial direct current stimulation (tDCS) can enhance cognitive function in healthy individuals, with promising applications as a therapeutic intervention. Despite this potential, variability in the efficacy of tDCS has been a considerable concern. OBJECTIVE:/Hypothesis: Given that tDCS is always applied at a set intensity, we examined whether individual differences in sensitivity to brain stimulation might be one variable that modulates the efficacy of tDCS in a motor learning task. METHODS:In the first part of the experiment, single-pulse transcranial magnetic stimulation (TMS) over primary motor cortex (M1) was used to determine each participant's resting motor threshold (rMT). This measure was used as a proxy of individual sensitivity to brain stimulation. In an experim

SUBMITTER: Labruna L 

PROVIDER: S-EPMC6592723 | biostudies-literature | 2019 Jul - Aug

REPOSITORIES: biostudies-literature