Genetic and Environmental Influences on Urinary Conditions in Men: A Classical Twin Study.

ABSTRACT:

Objective

To evaluate the genetic and environmental relationship among prostatitis and other urological conditions, including benign prostatic hyperplasia (BPH) and prostate cancer (CaP), a classical twin design and biometric modeling was used. While prostatitis-characterized by pain and voiding symptoms, no clear etiology, and functional and quality of life impairments-co-occurs with other urinary conditions, the degree of shared overlapping etiologic processes among them remains unclear. We examined the contribution of genetic and environmental factors to these conditions and the etiology of their associations at the level of genetic and environmental influences.

Methods

4380 monozygotic and dizygotic male twin pairs from the Vietnam Era Twin Registry reported lifetime phy

SUBMITTER: Gasperi M 

PROVIDER: S-EPMC6592774 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature