N-doped carbon nanodots@UiO-66-NH₂ as novel nanoparticles for releasing of the bioactive drug, rosmarinic acid and fluorescence imaging.

ABSTRACT:

Background and the purpose of the study

The purpose of the present research was to synthesize affordable nanoparticles for simultaneous drug release and cell fluorescence imaging to decrease the costs associated with conventional treatments.

Methods

In the present study, N-doped carbon nanodots@UiO-66-NH₂ nanoparticles were simply synthesized in few steps and were used as a novel carrier for rosmarinic acid (RA). Nano particles were characterized by FT-IR spectroscopy, X-ray powder diffraction (XRD), Dynamic Light Scattering (DLS) and field emission scanning electron microscopy (FE-SEM). UV/vis spectroscopy was used to study the release profile of RA drug from this novel carrier. Methylthiazolyl tetrazolium (MTT) assay was to evaluate the effect of irradiation wit

SUBMITTER: Tabatabaeian K 

PROVIDER: S-EPMC6592999 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature