Cost-effectiveness of an insertable cardiac monitor in a high-risk population in the UK.

ABSTRACT:

Objective

To evaluate the cost-effectiveness of insertable cardiac monitors (ICMs) compared with standard of care (SoC) for detecting atrial fibrillation (AF) in patients at high risk of stroke (CHADS₂ >2), using a UK National Health Service (NHS) perspective.

Methods

Using patient characteristics and clinical data from the REVEAL AF trial, a Markov model assessed the cost-effectiveness of detecting AF with an ICM compared with SoC. Costs and benefits were extrapolated across modelled patient lifetime. Ischaemic and haemorrhagic strokes, intracranial and extracranial haemorrhages and minor bleeds were modelled. Diagnostic and device costs were included, plus costs of treating stroke and bleeding events and costs of oral anticoagulants (OACs). Costs and health outc

SUBMITTER: Rinciog CI 

PROVIDER: S-EPMC6593196 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature