Diagnostic and prognostic values of serum activin-a levels in patients with acute respiratory distress syndrome.

ABSTRACT:

Background

We aimed to evaluate whether serum activin-A levels are elevated and have any value in predicting severity and prognosis in acute respiratory distress syndrome (ARDS).

Methods

Retrospective cohort study was performed with patients who were admitted to MICU with diagnosis of ARDS and have serum samples stored within 48 h of Intensive care unit (ICU) admission between March 2013 and December 2016 at a single tertiary referral hospital. Serum activin-A levels were measured with ELISA kit, and were compared with those of normal healthy control and non-ARDS sepsis patients.

Results

Total 97 ARDS patients were included for the study. Levels of Activin-A were elevated in ARDS patients compared to those of healthy controls (Log-transformed activin-A levels 2.89 ± 0

SUBMITTER: Kim JM 

PROVIDER: S-EPMC6593589 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature