Whole blood transcriptome analysis reveals footprints of cattle adaptation to sub-arctic conditions.

ABSTRACT: Indigenous cattle breeds in northern Eurasia have adapted to harsh climate conditions. The local breeds are important genetic resources with cultural and historical heritages, and therefore, their preservation and genetic characterization are important. In this study, we profiled the whole-blood transcriptome of two native breeds (Northern Finncattle and Yakutian cattle) and one commercial breed (Holstein) using high-throughput RNA sequencing. More than 15 000 genes were identified, of which two, 89 and 162 genes were significantly upregulated exclusively in Northern Finncattle, Yakutian cattle and Holstein cattle respectively. The functional classification of these significantly differentially expressed genes identified several biological processes and pathways related to signalling mecha

SUBMITTER: Pokharel K 

PROVIDER: S-EPMC6593690 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature