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Outcomes following pancreatic surgery using three different thromboprophylaxis regimens.


ABSTRACT:

Background

Postpancreatectomy haemorrhage (PPH) and venous thromboembolism (VTE) are serious complications following pancreatic surgery. The aim was to assess the timing, occurrence and predictors of PPH and VTE.

Methods

Elective pancreatic resections undertaken in a single university hospital between November 2013 and September 2017 were assessed. Three intervals were reviewed, each with a different routine regimen of nadroparin: 2850 units once daily (single dose) administered in hospital only, or 5700 units once daily (double dose) or 2850 units twice daily (split dose) administered in hospital and continued for 6 weeks after surgery. Clinically relevant PPH (CR-PPH) was classified according to International Study Group of Pancreatic Surgery criteria. VTE was defined acco

SUBMITTER: Hanna-Sawires RG 

PROVIDER: S-EPMC6593975 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature